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Product Information:

BMX-IN-3

BMX-IN-3 (B6a) is an irreversible and selective BMX inhibitor, with an IC50 of 12 nM. BMX-IN-3 (B6a) promots cell cycle arrest and apoptosis, triggers protective autophagy, and suppresses the BMX/AKT/mTOR pathway. BMX-IN-3 (B6a) can be used in the research for Gastric Carcinoma .

Cat. No.: EX-A16132    Purity: >98%
Chemical
Chemical structure of BMX-IN-3


For research only, Do not use for Human!

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CAS No.2657662-64-9
Purity>98%
FormulaC22H25N7O3S
Mol Weight467.544
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Nan Wang, Design, Synthesis, and Mechanism Study of Novel BMX Inhibitors Based on the Core of 1,3,5-Triazin-2-Amine for the Treatment of Gastric Carcinoma. J Med Chem. 2025 Feb 27;68(4):4196-4216.

CoACoA of BMX-IN-3
Smiles:N(C=1N=C(NC2=CC(OC3=CC=CC=C3)=CC=C2)N=C(N)N1)[C@H]4CN(S(C=C)(=O)=O)CCC4

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