BMV109

BMV109 is a quenched probe that becomes fluorescent when cleaved and covalently bound by active cathepsin proteases. BMV109 can be exploited for tumor imaging.


Cat. No.: EX-A13052	Purity: >98%

	Chemical structure of BMV109

For research only, Do not use for Human!

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CAS No.	1458731-58-2
Purity	>98%
Formula	C107H108F4N10O23S5
Mol Weight	2138.374
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Martijn Verdoes, et al. Improved quenched fluorescent probe for imaging of cysteine cathepsin activity. J Am Chem Soc. 2013 Oct 2;135(39):14726-30. [2]. Steven Sensarn, et al. A Clinical Wide-Field Fluorescence Endoscopic Device for Molecular Imaging Demonstrating Cathepsin Protease Activity in Colon Cancer. Mol Imaging Biol. 2016 Dec;18(6):820-829.
CoA	CoA of BMV109

Smiles:	S(=O)(=O)(C1=C(C=2C3=C([O+]=C4C2C=CC(=C4)N5C=6C(CC5)=CC(S(=O)(=O)O)=CC6)C=C(C=C3)N7C=8C(CC7)=CC(S(=O)(=O)[O-])=CC8)C=CC=C1)N9CCC(C(NCCNC(=O)C%10=C(F)C(F)=C(OCC([C@@H](NC([C@H](CC%11=CC=CC=C%11)NC(OCC%12=CC=CC=C%12)=O)=O)CCCCNC(CCCCCN%13C=%14C(C(C)(C)C%13=


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