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Product Information:

BMS5121458

BMS512148 (Dapagliflozin) is a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor.

Cat. No.: EX-A005    Purity: >99.5%
Chemical
Chemical structure of BMS5121458


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg330In-stock
1g520In-stock
2g780In-stock
31010In-stock
5g1300In-stock
10g2160In-stock


SynonymsDapagliflozin
CAS No.461432-26-8
Purity>99.5%
FormulaC21H25ClO6
Mol Weight408.873
Colorwhite to off-white
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Pedersen MG, et al. Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells. Sci Rep. 2016 Aug 18;6:31214.

[2]. Chiba Y, et al. Dapagliflozin, a Sodium-Glucose Co-Transporter 2 Inhibitor, Acutely Reduces Energy Expenditure in BAT via Neural Signals in Mice. PLoS One. 2016 Mar 10;11(3):e0150756.

[3]. Chang YK, et al. Dapagliflozin, SGLT2 Inhibitor, Attenuates Renal Ischemia-Reperfusion Injury. PLoS One. 2016 Jul 8;11(7):e0158810.

[4]. Meng, Wei et al. Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes. Journal of medicinal chemistry vol. 51,5 (2008): 1145-9.

CoACoA of BMS5121458
Smiles:CCOC1=CC=C(CC2=CC(=CC=C2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C1

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