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Product Information:

BMS-986339

BMS-986339 is a potent, selective farnesoid X receptor (FXR) agonist with EC50 of 34 nM (hFXR-Gal4), demonstrates differential induction of Fgf15 in the liver and ileum by FXR agonists in vivo.

Cat. No.: EX-A6649    Purity: >98%
Chemical
Chemical structure of BMS-986339


For research only, Do not use for Human!

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CAS No.2477873-64-4
Purity>98%
FormulaC35H41F4N3O4
Mol Weight643.7114
Color White to off-white
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Susheel J Nara, et al. Discovery of BMS-986339, a Pharmacologically Differentiated Farnesoid X Receptor Agonist for the Treatment of Nonalcoholic Steatohepatitis. J Med Chem. 2022 Jul 14;65(13):8948-8960.

CoACoA of BMS-986339

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