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Product Information:

BMS-986308

BMS-986308 is a selective and orally active renal outer medullary potassium (ROMK) channel inhibitor. BMS-986308 is selective for ROMK over hERG. BMS-986308 can be used for heart failure research .

Cat. No.: EX-A9251    Purity: >98%
Chemical
Chemical structure of BMS-986308


For research only, Do not use for Human!

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CAS No.2254333-97-4
Purity>98%
FormulaC24H25N7O2
Mol Weight443.501
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Jeremy M Richter, et al. Discovery of BMS-986308: A Renal Outer Medullary Potassium Channel Inhibitor for the Treatment of Heart Failure. J Med Chem. 2024 Jun 13;67(11):9731-9744.

CoACoA of BMS-986308
Smiles:CC=1C(=CC=C2C1COC2=O)[C@@H]3CN(CC4=NN(N=C4)C5=CC(C)=C(C#N)C=N5)C[C@H](C)N3

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