BMS-986278

BMS-986278 is a potent and orally active lysophosphatidic acid receptor 1 (LPA1) antagonist, with Kbs of 6.9 nM and 4.0 nM for human and mouse LPA1, respectively. BMS-986278 can be used for the research of pulmonary fibrotic disease.


Cat. No.: EX-A5516	Purity: >98%

	Chemical structure of BMS-986278

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	200	In-stock
250mg	400	In-stock
500mg	672	In-stock
1g	1056	In-stock
5g	get quote	In-stock
10g	get quote	In-stock

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Synonyms	Admilparant
CAS No.	2170126-74-4
Purity	>98%
Formula	C22H31N5O5
Mol Weight	445.512
Color	White to light yellow
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Cheng PTW, et, al. Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases. J Med Chem. 2021 Nov 11;64(21):15549-15581.
Data Sheet	Data sheet of BMS-986278
CoA	CoA of BMS-986278
SDS	SDS of BMS-986278

Smiles:	CC1=NC(C2=C(COC(N(C)CCC)=O)N(C)N=N2)=CC=C1O[C@@H]3C[C@@H](C(O)=O)CCC3


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