BMS-986224

BMS-986224 is a potent, selective and orally active APJ receptor agonist (Kd = 0.3 nM). BMS-986224 exhibits similar receptor binding and signaling profile to (Pyr 1) apelin-13. BMS-986224 has the potential for the research of heart failure .


Cat. No.: EX-A11429	Purity: >98%

	Chemical structure of BMS-986224

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	700	In-stock
250mg	1050	In-stock
500mg	1550	In-stock
1g	2150	In-stock

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CAS No.	2055200-88-7
Purity	>98%
Formula	C24H23ClN4O6
Mol Weight	498.916
Color	Off-white to light yellow
State	solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Gargalovic P, et al. In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure. Circ
CoA	CoA of BMS-986224

Smiles:	O=C1NC(COCC)=C(C2=C(OC)C=CC=C2OC)C(O)=C1C3=NN=C(CC4=NC=C(C=C4)Cl)O3


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