BMS 605541

BMS-605541 is a selective and orally active inhibitor of VEGFR-2 kinase with an IC50 value of 23 nM and Ki value of 49 nM. BMS-605541 inhibits the activity of Flk-1, VEGFR-1 and PDGFR-β with IC50 values of 40 nM, 400 nM and 200 nM, respectively. BMS-605541 can be used for cancer research[1].


Cat. No.: EX-A17168	Purity: >98%

	Chemical structure of BMS 605541

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	337	in_stock
500mg	543	in_stock
1g	847	in_stock
2g	1394	in_stock
3g	1608	in_stock
5g	2224	in_stock

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CAS No.	639858-32-5
Purity	>98%
Formula	C19H17F2N5OS
Mol Weight	401.433
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Borzilleri RM, et al. Discovery and evaluation of N-cyclopropyl- 2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5- ylmethyl)amino)benzamide (BMS-605541), a selective and orally efficacious inhibitor of vascular endothelial growth factor receptor-2. J Med Chem. 2006 Jun 29;49(13):3766-9.
CoA	CoA of BMS 605541

Smiles:	FC1=C(C=C(C(F)=C1)C(NC2CC2)=O)NCC3=CN=C(S3)NC4=NC=CC=C4


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