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Product Information:

BMS-191011

BMS 191011 is a maxi-K channel opener. Maxi-K channels consist of a pore-forming α subunit and a regulatory β subunit. Maxi-K channels are of a high Ca2+ sensitivity.

Cat. No.: EX-A4811    Purity: 98+%
Chemical
Chemical structure of BMS-191011


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg425In-stock
250mg675In-stock
500mg975In-stock


CAS No.202821-81-6
Purity98+%
FormulaC16H10ClF3N2O3
Mol Weight370.71
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Hewawasam P, Ding M, Chen N, et al. Synthesis of water-soluble prodrugs of BMS-191011: a maxi-K channel opener targeted for post-stroke neuroprotection. Bioorganic & medicinal chemistry letters, 2003, 13(10): 1695-1698.

[2]. Valverde MA, Rojas P, Amigo J, et al. Acute activation of Maxi-K channels (hSlo) by estradiol binding to the β subunit. Science, 1999, 285(5435): 1929-1931.
CoACoA of BMS-191011
Smiles:C1=CC(=CC=C1C2=NN(C(=O)O2)CC3=C(C=CC(=C3)Cl)O)C(F)(F)F

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