BMAP 28 (bovine) free acid

BMAP 28, bovine is an antibacterial peptide. BMAP 28, bovine exhibits antimicrobial activity against gram-positive and gram-negative bacteria, by increasing cell membrane permeability, and causing leakage of cell contents. BMAP 28, bovine exhibits cytotoxicity to cancer cells and activated human lymphocytes. BMAP 28, bovine induces apoptosis through depolarization of mitochondrial membrane potential .


Cat. No.: EX-A9828	Purity: >98%

	Chemical structure of BMAP 28 (bovine) free acid

For research only, Do not use for Human!

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CAS No.	939963-76-5
Purity	>98%
Formula	C147H252N44O31
Mol Weight	3131.85
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Brogden KA, et al., Antimicrobial peptides in animals and their role in host defences. Int J Antimicrob Agents. 2003 Nov;22(5):465-78. [2]. Guo Y, et al., A bovine myeloid antimicrobial peptide (BMAP-28) and its analogs kill pan-drug-resistant Acinetobacter baumannii by interacting with outer membrane protein A (OmpA). Medicine (Baltimore). 2018 Oct;97(42):e12832. [3]. Risso A, et al., BMAP-28, an antibiotic peptide of innate immunity, induces cell death through opening of the mitochondrial permeability transition pore. Mol Cell Biol. 2002 Mar;22(6):1926-35.
CoA	CoA of BMAP 28 (bovine) free acid

Smiles:	C([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(NCC(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(O)=O)=O)[C@H](CC)C)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCC3)C(C)C)=O)[C@H](CC)C)=O)[C@H](CC)C)


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