BLU-9931

BLU9931 is a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 3 nM and a Kd of 6 nM. BLU9931 has significant antitumor activity.


Cat. No.: EX-A608	Purity: >98%

	Chemical structure of BLU-9931

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	583	in_stock
1g	1023	in_stock
2g	1754	inquire
5g	3557	inquire

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CAS No.	1538604-68-0
Purity	>98%
Formula	C26H22Cl2N4O3
Mol Weight	509.384
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hagel M, et al. First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway. Cancer Discov. 2015 Apr;5(4):424-37.
CoA	CoA of BLU-9931

Smiles:	COC1=CC(OC)=C(Cl)C(C2=CC3=CN=C(NC4=C(C)C=CC=C4NC(=O)C=C)N=C3C=C2)=C1Cl


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