BL-918

BL-918 is an orally active UNC-51-like kinase 1 (ULK1) activator with an EC50 of 24.14 nM. BL-918 exerts its cytoprotective autophagic effect by targeting ULK complex. BL-918 has the potential for Parkinson's disease (PD) treatment.


Cat. No.: EX-A3463	Purity: >98%

	Chemical structure of BL-918

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	585	In-stock
1g	880	In-stock
5g	3300	In-stock
10g	4880	In-stock

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Synonyms	BL918
Synonyms 2	BL 918
CAS No.	2101517-69-3
Purity	>98%
Formula	C23H15F8N3OS
Mol Weight	533.437
State	solid powder
Solubility	Soluble in DMSO >100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Ouyang L, et al. Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective Autophagy for Parkinson's Disease Treatment. J Med Chem. 2018 Apr 12;61(7):2776-2792.
CoA	CoA of BL-918

Smiles:	O=C(NC1=CC=C(F)C=C1F)[C@H](NC(NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=S)C3=CC=CC=C3


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