Bisindolylmaleimide IV

Bisindolylmaleimide IV (Arcyriarubin A) is a potent protein kinase C (PKC) inhibitor, with IC50s ranging from 0.1 to 0.55 μM. Bisindolylmaleimide IV also inhibits PKA (IC50=3.1-11.8μM) . Bisindolylmaleimide IV is a potent, selective inhibitor of human cytomegalovirus (HCMV) replication in cell culture with an IC50 of 0.2 μM .


Cat. No.: EX-A17502	Purity: >98%

	Chemical structure of Bisindolylmaleimide IV

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	426	in_stock
250mg	853	in_stock
500mg	1385	in_stock
1g	2182	in_stock
2g	3490	in_stock
3g	4165	in_stock

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CAS No.	119139-23-0
Purity	>98%
Formula	C20H13N3O2
Mol Weight	327.3361
Color	Orange to red
State	Solid
Solubility	DMSO : 125 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Davis PD, et al. Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides. J Med Chem. 1992 Jan;35(1):177-84. [2].Slater MJ, et al. Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication. Bioorg Med Chem. 1999 Jun;7(6):1067-74.
CoA	CoA of Bisindolylmaleimide IV

Smiles:	O=C(C(C1=CNC2=C1C=CC=C2)=C3C4=CNC5=C4C=CC=C5)NC3=O


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