BIMAX2

BIMAX2 is a high affinity nuclear localization signal (NLS) peptide. BIMAX2 can mimic the activity of the classical nuclear localization signal (cNLS) and competitively bind to importin α, thereby inhibiting the binding of cNLS-cargo proteins to importin α. BIMAX2 can be used to study the role of RBBP4 in regulating nuclear import efficiency and cell senescence .


Cat. No.: EX-A9818	Purity: >98%

	Chemical structure of BIMAX2

For research only, Do not use for Human!

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CAS No.	1105053-46-0
Purity	>98%
Formula	C146H254N64O41
Mol Weight	3561.9832
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Tsujii, et al. "Retinoblastoma-binding protein 4-regulated classical nuclear transport is involved in cellular senescence." Journal of Biological Chemistry 290.49 (2015): 29375-29388.
CoA	CoA of BIMAX2

Smiles:	C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCNC(=N)N)=O)CCC(O)


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