Bilobalide

Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons.


Cat. No.: EX-A6793	Purity: >98%

	Chemical structure of Bilobalide

For research only, Do not use for Human!

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Synonyms	Bilobalid
Synonyms 2	(-)-Bilobalide
CAS No.	33570-04-6
Purity	>98%
Formula	C15H18O8
Mol Weight	326.2986
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO ? 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years, 4°C 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. O Weichel, et al. Bilobalide, a constituent of Ginkgo biloba, inhibits NMDA-induced phospholipase A2 activation and phospholipid breakdown in rat hippocampus. Naunyn Schmiedebergs Arch Pharmacol. 1999 Dec;360(6):609-15. [2]. Chun Shi, et al. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Apoptosis. 2010 Jun;15(6):715-27.
CoA	CoA of Bilobalide


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