BIBP3226 TFA

BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect.


Cat. No.: EX-A11237	Purity: >98%

	Chemical structure of BIBP3226 TFA

For research only, Do not use for Human!

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CAS No.	1068148-47-9
Purity	>98%
Formula	C29H32F3N5O5
Mol Weight	587.5901
Color	White to off-white
State	solid
Solubility	DMSO : 250 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -80°C 2 years; -20°C 1 year; Sealed storage, away from moisture and light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Mollereau C, et al. Agonist and antagonist activities on human NPFF(2) receptors of the NPY ligands GR231118 and BIBP3226. Br J Pharmacol. 2001 May;133(1):1-4. [2]. Kask A, et al. Anxiogenic-like effect of the neuropeptide Y Y1 receptor antagonist BIBP3226: antagonism with diazepam. Eur J Pharmacol. 1996 Dec 19;317(2-3):R3-4.
CoA	CoA of BIBP3226 TFA

Smiles:	FC(C(O)=O)(F)F.OC(C=C1)=CC=C1CNC([C@@H](CCCNC(N)=N)NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)=O


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