BI-749327

BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively.


Cat. No.: EX-A4692	Purity: >98%

	Chemical structure of BI-749327

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	650	In-stock
250mg	950	In-stock
500mg	1450	In-stock
1g	2250	In-stock
5g	7875	In-stock

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Synonyms	BI749327
CAS No.	2361241-23-6
Purity	>98%
Formula	C23H21F3N4O2
Mol Weight	442.4336
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lin B L, et al. In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease. Proc Natl Acad Sci U S A. 2019 May 14;116(20):10156-10161.
CoA	CoA of BI-749327

Smiles:	NC1=NN=C(C2CCN(C(C3=CC=C(OC4=CC=C(C(F)(F)F)C=C4)C=C3)=O)CC2)C=C1


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