BI-4916

BI-4916 is a proagent of BI-4924. BI-4924 is a NADH/NAD+-competitive PHGDH inhibitor. BI-4916 inhibits cancer cell migration. BI-4916 can be used for cancer, inflammation and infection study.


Cat. No.: EX-A5586	Purity: >98%

	Chemical structure of BI-4916

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	2244451-48-5
Purity	>98%
Formula	C23H24Cl2N2O6S
Mol Weight	527.417
Color	White to yellow
State	solid powder
Solubility	Soluble in DMSO 250 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years, 4°C 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs

Reference:	[1]. Weinstabl H, et al. Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis. J Med Chem. 2019 Jul 31. [2]. Kiweler N, et al. Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis. Nat Commun. 2022 May 16;13(1):2699. [3]. Becker B, et al. Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut. iScience. 2024 Feb 8;27(3):109173.
CoA	CoA of BI-4916


		Search