BI-4732

BI-4732 a potent inhibitor EGFR-activating (E19del and L858R) and T790M mutations, with high blood-brian barrier penetration, targeting a broad range of EGFR mutations, including C797S. BI-4732 has anti-tumor activity.


Cat. No.: EX-A9730	Purity: >98%

	Chemical structure of BI-4732

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	2100	Inquire
100mg	3225	Inquire
250mg	get quote	Inquire
500mg	get quote	Inquire
1g	get quote	Inquire

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CAS No.	2769715-68-4
Purity	>98%
Formula	C32H36N10O2
Mol Weight	592.694
Color	light yellow to yellow
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, 2 years, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Eun Ji Lee, et al. Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC. Clin Cancer Res. 2024 Feb 8.
CoA	CoA of BI-4732

Smiles:	CN1C=2C(=C(N=C(C2)N3C=4C(C=N3)=C(C)N=C(C4)C=5C(OC)=CC=NC5)N6[C@@]7(C[C@](C6)(OC7)[H])[H])N=C1N8C[C@@]9(N(CC8)CCC9)[H]


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