BI-2865

BI-2865 is a pan-KRAS inhibitor. BI-2865 inhibited the proliferation of isogenic G12C, G12D or G12V mutant KRAS expressing BaF3 cells more potently than precursor 1 with a mean IC50 of roughly 140 nM.


Cat. No.: EX-A6987A	Purity: >98%

	Chemical structure of BI-2865

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	785	In-stock
100mg	1000	In-stock
250mg	1500	In-stock
500mg	2200	In-stock
1g	3200	In-stock
5g	get quote	In-stock

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CAS No.	2937327-93-8
Purity	>98%
Formula	C23H27N7O2S
Mol Weight	465.571
Color	Light yellow to brown
State	solid powder
Solubility	DMSO : 250 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kim, Dongsung et al. “Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.” Nature, 10.1038/s41586-023-06123-3. 31 May. 2023
CoA	CoA of BI-2865


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