BI-0115

BI-0115 is a selective inhibitor of LOX-1 (IC50=5.4 μM) that blocks cellular uptake of oxLDL. BI-0115 binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain.


Cat. No.: EX-A5939	Purity: >98%

	Chemical structure of BI-0115

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	550	In-stock
50mg	785	In-stock
100mg	1250	In-stock
200mg	1850	In-stock

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CAS No.	4929-23-1
Purity	>98%
Formula	C15H14ClN3O
Mol Weight	287.744
Color	Light yellow to yellow
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C 3 years, 4°C 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Schnapp, G., et al. A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer state. Commun Chem 3, 75 (2020).
CoA	CoA of BI-0115


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