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Product Information:

BHPI

BHPI is a nuclear receptor ERα inhibitor. BHPI activates PLCγ and UPR. BHPI has antitumor activity against breast, endometrial, and ovarian cancers[1][2].

Cat. No.: EX-A14449    Purity: >98%
Chemical
Chemical structure of BHPI


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg498In-stock
250mg836In-stock
500mg1256In-stock
1g1928In-stock
5gget quoteInquire


CAS No.56632-39-4
Purity>98%
FormulaC21H17NO3
Mol Weight331.3646
ColorWhite to off-white
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 year;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Andruska ND, et al. Estrogen receptor α inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regression. Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4737-42.

[2]. Mao C, et al. Antiestrogen Resistant Cell Lines Expressing Estrogen Receptor α Mutations Upregulate the Unfolded Protein Response and are Killed by BHPI. Sci Rep. 2016 Oct 7;6:34753.

CoACoA of BHPI
Smiles:CC1=C2C(=CC=C1)C(C(=O)N2)(C3=CC=C(C=C3)O)C4=CC=C(C=C4)O

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