BGT226 maleate

BGT226 maleate (NVP-BGT226 maleate) is a PI3K/mTOR dual inhibitor which displays potent growth-inhibitory activity against human head and neck cancer cells.


Cat. No.: EX-A3431	Purity: >98%

	Chemical structure of BGT226 maleate

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	400	In-stock
250mg	750	In-stock
500mg	1100	In-stock
1g	1500	In-stock
2g	2500	In-stock
5g	4900	In-stock

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Synonyms	NVP-BGT226 maleate
CAS No.	1245537-68-1
Purity	>98%
Formula	C32H29F3N6O6
Mol Weight	650.6045
State	solid powder
Solubility	Soluble in DMSO, not in water
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Markman B, et al. Phase I safety, pharmacokinetic, and pharmacodynamic study of the oral phosphatidylinositol-3-kinase and mTOR inhibitor BGT226 in patients with advanced solid tumors. Ann Oncol. 2012 Sep;23(9):2399-408. [2]. Chang KY, et al. Novel phosphoinositide 3-kinase/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo. Clin Cancer Res. 2011 Nov 15;17(22):7116-26.
CoA	CoA of BGT226 maleate

Smiles:	COC1=CC=C(C=N1)C2=CC=C(C3=C2)N=CC(N4C)=C3N(C4=O)C5=CC=C(C(C(F)(F)F)=C5)N6CCNCC6.OC(/C=C\C(O)=O)=O


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