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Product Information:

BGB116673

BGB‐16673 is an investigational BTK‐targeting chimeric degradation activation compound (CDAC) active against both wild‐type and mutant BTK.

Cat. No.: EX-A8331    Purity: >98%
Chemical
Chemical structure of BGB116673


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg617in_stock
100mg886in_stock
250mg1641in_stock
500mg2976in_stock
1g5367in_stock
5g20704in_stock


SynonymsBGB-116673
CAS No.2736508-60-2
Purity>98%
FormulaC47H54N12O4
Mol Weight851.0097
ColorLight yellow to green yellow
Statesolid powder
SolubilityDMSO : 125 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Hexiang Wang, et al. Degradation of bruton's tyrosine kinase (btk) by conjugation of btk inhibitors with e3 ligase ligand and methods of use. WO2021219070A1. 2021-11-04.

Data SheetData sheet of BGB116673
CoACoA of BGB116673
SDSSDS of BGB116673
Smiles:C[C@H](C1=C(C=C(C2=C3C=C(C4=CN=C(N5CCN(CC5)CC6CCN(C7=CC=C(N8CCC(NC8=O)=O)C=C7)CC6)C=C4)NC3=NC=N2)C=C1)C)NC(C9=NC(C(C)(C)C)=NO9)=O

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