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Product Information:

BGB-116673 analog

BGB-116673 analog is an investigational BTK‐targeting chimeric degradation activation compound (CDAC) active against both wild‐type and mutant BTK.

Cat. No.: EX-A8331A    Purity: >98%
Chemical
Chemical structure of BGB-116673 analog


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg487in_stock
250mg922in_stock
500mg2022in_stock
1g2772in_stock
2g5036in_stock
5g10278in_stock


SynonymsBGB116673 analog
Synonyms 2BTK-inhibitor
CAS No.2736508-94-2
Purity>98%
FormulaC48H55N11O4
Mol Weight850.0216
Color>3 years if stored properly
SolubilityPowder 4? 2 years; In solvent -20? 1 month;
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Hexiang Wang, et al. Degradation of bruton's tyrosine kinase (btk) by conjugation of btk inhibitors with e3 ligase ligand and methods of use. WO2021219070A1. 2021-11-04.

CoACoA of BGB-116673 analog
Smiles:C[C@@H](NC(=O)C1=NC(=NO1)C(C)(C)C)C1=CC=C(C=C1C)C1=C2C=C(NC2=NC=N1)C1=CC=C(N=C1)N1CCN(CC2CCN(CC2)C2=CC=C(C=C2)C2CCC(=O)NC2=O)CC1

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