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Product Information:

BGB-102

BGB-102 (JNJ-26483327) is a potent multi-kinase inhibitor against EGFR, HER2, and HER4 with IC50s of 9.6 nM, 18 nM and 40.3 nM, respectively.

Cat. No.: EX-A8458    Purity: >98%
Chemical
Chemical structure of BGB-102


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg800Inquire
50mg2200In-stock
100mg3000In-stock
250mgget quoteIn-stock
500mgget quoteIn-stock
1gget quoteIn-stock


SynonymsJNJ-26483327
CAS No.807640-87-5
Purity>98%
FormulaC22H25BrN4O2
Mol Weight457.364
ColorWhite to off-white
Statesolid powder
SolubilityTHF : ? 7.27 mg/mL DMSO : 4.4 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent   -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Gijsen M, et al. HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer. PLoS Biol. 2010 Dec 21;8(12):e1000563.

CoACoA of BGB-102
Smiles:COC1=CC2=NC=NC3=C2C=C1OCCCCCN(CC4=CC=C(C=C4N3)Br)C

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