background


Product Information:

Berotralstat

Berotralstat (BCX7353) is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE.

Cat. No.: EX-A5537    Purity: >98%
Chemical
Chemical structure of Berotralstat


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mgget quoteInquire
500mgget quoteInquire
1gget quoteInquire
2gget quoteInquire
3gget quoteInquire
5gget quoteInquire


SynonymsBCX7353
Synonyms 2BCX 7353
CAS No.1809010-50-1
Purity>98%
FormulaC30H26F4N6O
Mol Weight562.5607
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, stored under nitrogen; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Zuraw B, et al. Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial [published online ahead of print, 2020 Oct 21]. J Allergy Clin Immunol. 2020;S0091-6749(20)31484

[2]. Manning ME, et al. Berotralstat (BCX7353) is a novel oral prophylactic treatment for hereditary angioedema: Review of phase II and III studies. Allergy Asthma Proc. 2021;42(4):274-282.

CoACoA of Berotralstat

KEYWORDS: buy Berotralstat | Berotralstat supplier | purchase | cost | manufacturer | order | distributor | buy 1809010-50-1 | 1809010-50-1 supplier