Berkeleyacetal C

keleyacetal C, a meroterpenoid compound with anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways. Berkeleyacetal C significantly inhibits the expression of iNOS and the following NO production by macrophages. Berkeleyacetal C inhibits expression and secretion of key pro-inflammatory factors and chemokines (TNF-α, IL-6, IL-1β, MIP-1α, and MCP-1). Berkeleyacetal C also inhibits activation of neutrophils and reactive oxygen species (ROS) production. Berkeleyacetal C can be used for the study of inflammatory disorders .


Cat. No.: EX-A16390	Purity: >98%

	Chemical structure of Berkeleyacetal C

For research only, Do not use for Human!

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CAS No.	959772-67-9
Purity	>98%
Formula	C24H26O8
Mol Weight	442.4584
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Li SS, et al. Berkeleyacetal C, a meroterpenoid isolated from the fungus Penicillium purpurogenum MHZ 111, exerts anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways. Eur J Pharmacol. 2017;814:283-293.
CoA	CoA of Berkeleyacetal C

Smiles:	C[C@@]12[C@]([C@@]3(C=4C(=CC1=O)C(C)(C)OC(=O)C4)CO3)(C[C@]5(C)[C@@]6([C@]2(C(=O)[C@H](C)O[C@@]6(OC5=O)[H])[H])[H])[H]


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