BEN-28010

BEN-28010 is a selective, orally active, blood-brain barrier permeable CHK1 inhibitor with an IC50 of 4.0 nM. BEN-28010 functions as a radiosensitizer, exhibits antitumor efficacy in GBM models. BEN-28010 can be used for the research of glioblastoma .


Cat. No.: EX-A16562	Purity: >98%

	Chemical structure of BEN-28010

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


Synonyms	BEN 28010
CAS No.	3033961-38-2
Purity	>98%
Formula	C20H22N8
Mol Weight	374.4423
State	Solid powder

Reference:	[1].Rawling MJ, et al. Discovery of a Potent, Selective, and Brain-Penetrant Checkpoint Kinase 1 Inhibitor, BEN-28010, for the Treatment of Glioblastoma. J Med Chem. 2025;68(9):9101-9125.
CoA	CoA of BEN-28010

Smiles:	N(C1=CN(C=N1)C2=CC=C(C=C2)N3C[C@H](N(C)C)CC3)C=4C=NC(C#N)=CN4


		Search