Belvarafenib TFA

Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively.


Cat. No.: EX-A9095	Purity: >98%

	Chemical structure of Belvarafenib TFA

For research only, Do not use for Human!

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Synonyms	HM95573 TFA
Synonyms 2	GDC-5573 TFA
CAS No.	2443966-84-3
Purity	>98%
Formula	C25H17ClF4N6O3S
Mol Weight	592.952
Color	Off-white to yellow
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, stored under nitrogen; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. WO 2013/100632 A1.
CoA	CoA of Belvarafenib TFA

Smiles:	O=C(C(C1=NC=N2)=CSC1=C2N)NC(C3=C4C(NC(C=CC=C5Cl)=C5F)=NC=C3)=C(C=C4)C.OC(C(F)(F)F)=O


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