BCFTP

BCFTP is a potent, orally active and selective human Mas-related G protein-coupled receptor X1 (MrgprX1)-positive allosteric modulator. BCFTP selectively potentiates MrgprX1 signaling in HEK293 cells. BCFTP alleviates specific neuropathic pain-related behaviors in a humanized MrgprX1 mouse model of chronic constrictive injury (CCI) in a MrgprX1-dependent manner. BCFTP synergistically enhances psychoactive substances analgesia in CCI MrgprX1 mice. BCFTP can be used for neuropathic pain research .


Cat. No.: EX-A16877	Purity: >98%

	Chemical structure of BCFTP

For research only, Do not use for Human!

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50mg	get quote

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CAS No.	2781215-95-8
Purity	>98%
Formula	C23H17ClF4N2O2S
Mol Weight	496.905
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Uniyal A, et al. An orally bioavailable MrgprX1-positive allosteric modulator alleviates certain neuropathic pain-related behaviors in humanized mice. Sci Transl Med. 2025 Dec 17;17(829):eadw9446.
CoA	CoA of BCFTP

Smiles:	CC(C)(C)C1=C(C2=CC=C(Cl)C=C2)C3=C(S1)N=CN=C3OC4=C(F)C=CC=C4OC(F)(F)F


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