BC1618

BC1618, an orally active Fbxo48 inhibitory compound, stimulates Ampk-dependent signaling (via preventing activated pAmpkα from Fbxo48-mediated degradation). BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity.


Cat. No.: EX-A5108	Purity: >98%

	Chemical structure of BC1618

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	350	In-stock
250mg	550	In-stock
500mg	850	In-stock
1g	1150	In-stock
5g	3250	In-stock

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Synonyms	BC-1618
CAS No.	2222094-18-8
Purity	>98%
Formula	C24H24F3NO2
Mol Weight	415.4481
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL H2O < 0.1 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Yuan Liu, et al. A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance. Nat Chem Biol. 2021 Mar;17(3):298-306.
CoA	CoA of BC1618

Smiles:	OC(COC1=CC=C(C(F)(F)F)C=C1)CN(CC2=CC=CC=C2)CC3=CC=CC=C3


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