Bazedoxifene acetate

Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer.


Cat. No.: EX-A5414	Purity: >99%

	Chemical structure of Bazedoxifene acetate

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	285	In-stock
1g	385	In-stock
5g	1050	In-stock
10g	1550	In-stock
20g	2150	In-stock

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CAS No.	198481-33-3
Purity	>99%
Formula	C32H38N2O5
Mol Weight	530.6545
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO? 100 mg/mL H2O < 0.1 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture and light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Barry S Komm, et al. Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology. 2005 Sep;146(9):3999-4008. [2]. Xiaojuan Wu, et al. Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy. Mol Cancer Ther. 2016 Nov; 15(11): 2609–2619.
CoA	CoA of Bazedoxifene acetate


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