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Product Information:

BAY-524

BAY-524 is a potent Bub1 kinase inhibitor. BAY-524 inhibits the recombinant catalytic domain of human Bub1 with an IC50 of 450 nM. BAY-524 can be used for the research of anti-cancer in combination with other agents.

Cat. No.: EX-A11240    Purity: >98%
Chemical
Chemical structure of BAY-524


For research only, Do not use for Human!

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CAS No.1445830-39-6
Purity>98%
FormulaC24H24F2N6O3
Mol Weight482.4826
ColorOff-white to light yellow
Statesolid
SolubilityDMSO : 166.67 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Baron AP, et al. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. Elife. 2016 Feb 17;5. pii: e12187.

CoACoA of BAY-524
Smiles:COC1=CN=C(C2=NN(CC3=C(F)C=C(OCC)C=C3F)C(OC)=C2C)N=C1NC4=CC=NC=C4

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