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Product Information:

BAY-320

BAY-320 is a Bub1 inhibitor, with an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.

Cat. No.: EX-A8657    Purity: >98%
Chemical
Chemical structure of BAY-320


For research only, Do not use for Human!

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CAS No.1445830-50-1
Purity>98%
FormulaC26H26F2N6O2
Mol Weight492.5204
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : 83.33 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent   -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Amalina I, et al. Inhibitors of the Bub1 spindle assembly checkpoint kinase: synthesis of BAY-320 and comparison with 2OH-BNPP1. R Soc Open Sci. 2021 Dec 15;8(12):210854.

[2].Baron AP, et al. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. Elife. 2016 Feb 17;5. pii: e12187.

CoACoA of BAY-320
Smiles:COC1=CN=C(C2=NN(CC3=C(F)C=C(OCC)C=C3F)C(C4CC4)=C2C)N=C1NC5=CC=NC=C5

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