Bavarostat

Bavarostat (EKZ-001) is a BBB-penetrable and selective HDAC6 inhibitor (IC50: 0.06 μM). Bavarostat modulates tubulin acetylation selectively over histone acetylation. Bavarostat can be used for research of cancers and central nervous system (CNS) disorders[1].


Cat. No.: EX-A14889	Purity: >98%

	Chemical structure of Bavarostat

For research only, Do not use for Human!

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Synonyms	EKZ-001
CAS No.	2134109-20-7
Purity	>98%
Formula	C20H27FN2O2
Mol Weight	346.439
Color	Light yellow to yellow
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Strebl MG, et al. HDAC6 Brain Mapping with [18F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination. ACS Cent Sci. 2017 Sep 27;3(9):1006-1014.
CoA	CoA of Bavarostat

Smiles:	CN(CC1=C(C=C(C=C1)C(=O)NO)F)CC23CC4CC(C2)CC(C4)C3


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