BAR-072

BAR-072 is a small-molecule inhibitor targeting TraE, with a KD of 2.7 µM. It significantly inhibits the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 shows promise as a candidate compound for blocking the spread of bacterial resistance genes and holds potential for research in infectious disease and antimicrobial resistance control.


Cat. No.: EX-A12513	Purity: >98%

	Chemical structure of BAR-072

For research only, Do not use for Human!

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CAS No.	2068867-65-0
Purity	>98%
Formula	C18H13N3O6
Mol Weight	367.3123
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Casu B, et al. Structural Analysis and Inhibition of TraE from the pKM101 Type IV Secretion System. J Biol Chem. 2016 Nov 4;291(45):23817-23829.
CoA	CoA of BAR-072

Smiles:	O=C(NN=CC=1OC(=CC1)C=2C=CC=CC2N(=O)=O)C3=CC(O)=CC=C3O


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