β-Catenin modulator-7

β-Catenin modulator-7 (Compound 5) is a modulator for β-catenin. β-Catenin modulator-7 inhibits the expression of β-catenin in HCT-116 cytoplasm and nucleus, suppresses the phosphorylation of GSK 3β. β-Catenin modulator-7 promotes NO release in HCT-116, and inhibits the proliferation of cancer cell HCT-116 with IC50 of 0.6-0.9 μM. β-Catenin modulator-7 can be used in reasearch about colon cancer.


Cat. No.: EX-A13185	Purity: >98%

	Chemical structure of β-Catenin modulator-7

For research only, Do not use for Human!

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Synonyms	beta-Catenin modulator-7
CAS No.	2892294-93-6
Purity	>98%
Formula	C26H35ClN4O9
Mol Weight	583.031
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zou Y, et al., Discovery of Cytotoxic Nitric Oxide-Releasing Piperlongumine Derivatives Targeting Wnt/β-Catenin in Colon Cancer Cells. J Nat Prod. 2024 Jul 24.
CoA	CoA of β-Catenin modulator-7

Smiles:	[O-]/[N+](N(CC)CC)=N\OCOC(CCCCOC1=C(OC)C=C(/C=C/C(N(CCC=C2Cl)C2=O)=O)C=C1OC)=O


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