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β-Amyrenonol

β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids .

Cat. No.: EX-A10414    Purity: >98%
Chemical
Chemical structure of β-Amyrenonol


For research only, Do not use for Human!

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Synonyms11-Oxo-β-amyrin
Synonyms 2beta-amyrenonol
CAS No.38242-02-3
Purity>98%
FormulaC30H48O2
Mol Weight440.7009
ColorWhite to off-white
StateSolid
StoragePowder 4°C, protect from light; In solvent -20°C, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. James Reed, et al. A Translational Synthetic Biology Platform for Rapid Access to Gram-Scale Quantities of Novel Drug-Like Molecules. Metab Eng. 2017 Jul;42:185-193.

[2]. Ming Zhu, et al. Boosting 11-oxo-β-amyrin and Glycyrrhetinic Acid Synthesis in Saccharomyces Cerevisiae via Pairing Novel Oxidation and Reduction System From Legume Plants. Metab Eng. 2018 Jan;45:43-50.

[3]. Hikaru Seki, et al. Licorice Beta-Amyrin 11-oxidase, a Cytochrome P450 With a Key Role in the Biosynthesis of the Triterpene Sweetener Glycyrrhizin. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14204-9.

CoACoA of β-Amyrenonol
Smiles:C[C@@]1([C@@]2([H])[C@@]3([C@@](C(C)([C@@H](O)CC3)C)([H])CC1)C)[C@]4(C([C@@]5([H])[C@](C)(CCC(C)(C)C5)CC4)=CC2=O)C

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