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Product Information:

Azumolene

Azumolene, EU4093, is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum.

Cat. No.: EX-A4755    Purity: >98%
Chemical
Chemical structure of Azumolene


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg500In-stock
100mg750In-stock
500mgget quoteIn-stock
1gget quoteIn-stock
5gget quote


SynonymsEU4093 free base
CAS No.64748-79-4
Purity>98%
FormulaC13H9BrN4O3
Mol Weight349.14
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Si D, Azam MA, Lai PFH, Zamiri N, Kichigina G, Asta J, Massé S, Bokhari MM, Porta-Sánchez A, Labos C, Sun H, Yang P, Nanthakumar K. Essential role of ryanodine receptor 2 phosphorylation in the effect of azumolene on ventricular arrhythmia vulnerability in a rabbit heart model. J Cardiovasc Electrophysiol. 2018 Dec;29(12):1707-1715. doi: 10.1111/jce.13737. Epub 2018 Oct 31. PMID: 30203424.

[2]. Talbert EE, Smuder AJ, Kwon OS, Sollanek KJ, Wiggs MP, Powers SK. Blockage of the Ryanodine Receptor via Azumolene Does Not Prevent Mechanical Ventilation- Induced Diaphragm Atrophy. PLoS One. 2016 Feb 5;11(2):e0148161. doi: 10.1371/journal.pone.0148161. PMID: 26849371; PMCID: PMC4744044.

[3]. Zhao X, Min CK, Ko JK, Parness J, Kim DH, Weisleder N, Ma J. Increased store- operated Ca2+ entry in skeletal muscle with reduced calsequestrin-1 expression. Biophys J. 2010 Sep 8;99(5):1556-64. doi: 10.1016/j.bpj.2010.06.050. PMID: 20816068; PMCID: PMC2931717.
CoACoA of Azumolene
Smiles:O=C1NC(CN1/N=C/C2=NC=C(C3=CC=C(Br)C=C3)O2)=O

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