Azidocillin

Azidocillin, a semi-synthetic Penicillin, is an orally active β-lactam antibiotic. Azidocillin bears an azide functionality and retains on-target activity within bacteria. Azidocillin can be used to research osteitis caused by dental surgery, otitis media, enterococcal septicemia and other bacterial infectious diseases[1][2][3]. Azidocillin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.


Cat. No.: EX-A14870	Purity: >98%

	Chemical structure of Azidocillin

For research only, Do not use for Human!

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CAS No.	17243-38-8
Purity	>98%
Formula	C16H17N5O4S
Mol Weight	375.402
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Bystedt H, et al. Concentration of azidocillin, erythromycin, doxycycline and clindamycin in dental alveolar serum after single oral doses. Int J Oral Surg. 1977 Apr;6(2):65-74. [2]. Spangler B, et al. Molecular Probes for the Determination of Subcellular Compound Exposure Profiles in Gram-Negative Bacteria. ACS Infect Dis. 2018 Sep 14;4(9):1355-1367. [3]. Bengtsson E, et al. Azidocillin treatment of enterococcal septicemia. Scand J Infect Dis. 1972;4(2):143-8.
CoA	CoA of Azidocillin

Smiles:	CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N=[N+]=[N-])C(=O)O)C


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