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Product Information:

AZD5423

AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM). AZD5423 effectively reduces allergen-induced responses in subjects with mild allergic asthma.

Cat. No.: EX-A5022    Purity: >98%
Chemical
Chemical structure of AZD5423


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg500Inquire
100mg785In-stock
250mg1185In-stock
500mg1885Inquire


SynonymsAZD-5423
CAS No.1034148-04-3
Purity>98%
FormulaC25H21F4N3O3
Mol Weight487.4462
Color White to yellow
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Werkström V, et al. Safety, Pharmacokinetics and Pharmacodynamics of the Selective Glucocorticoid Receptor Modulator AZD5423 after Inhalation in Healthy Volunteers. Basic Clin Pharmacol Toxicol. 2016 Dec;119(6):574-581.

[2]. Gauvreau GM, et al. A nonsteroidal glucocorticoid receptor agonist inhibits allergen-induced late asthmatic responses. Am J Respir Crit Care Med. 2015 Jan 15;191(2):161-7.

CoACoA of AZD5423
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