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Product Information:

AZD3759

AZD3759 is a potent, orally active, central nervous system-penetrant, EGFR inhibitor.

Cat. No.: EX-A720    Purity: >99%
Chemical
Chemical structure of AZD3759


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10g504in_stock


SynonymsZorifertinib
CAS No.1626387-80-1
Purity>99%
FormulaC22H23ClFN5O3
Mol Weight459.901
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Zeng Q, et al. Discovery and Evaluation of Clinical Candidate AZD3759, a Potent, Oral Active, Central Nervous System-Penetrant, Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor. J Med Chem. 2015 Oct 22;58(20):8200-15.

CoACoA of AZD3759
Smiles:COC1=CC2=NC=NC(NC3=CC=CC(Cl)=C3F)=C2C=C1OC(=O)N1CCN(C)C[C@H]1C

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