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Product Information:

AZD3293

Lanabecestat (AZD3293) is an oral beta-secretase 1 cleaving enzyme (BACE) inhibitor with an inhibitory constant Ki  of 0.4 nM.

Cat. No.: EX-A1471    Purity: >98%
Chemical
Chemical structure of AZD3293


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg700In-stock
100mg1080In-stock
200mg1550In-stock
1g3800In-stock


SynonymsLanabecestat
CAS No.1383982-64-6
Purity>98%
FormulaC26H28N4O
Mol Weight412.5267
Statesolid powder
Solubilitysoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. ketjäll, Susanna et al. AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics. Journal of Alzheimer's disease : JAD vol. 50,4 (2016): 1109-23.

CoACoA of AZD3293
Smiles:COC1CC[C@]2(CC3=CC=C(C=C3[C@@]22N=C(C)C(N)=N2)C2=CC(=CN=C2)C#CC)CC1

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