AZD-5718

Atuliflapon (AZD5718) is an orally active inhibitor of FLAP (5‑Lipoxygenase activating protein), with an IC50 of 2 nM. Atuliflapon is used in the study for coronary artery disease.


Cat. No.: EX-A8054	Purity: >98%

	Chemical structure of AZD-5718

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	685	In-stock
250mg	1250	In-stock
500mg	1850	In-stock
1g	2550	In-stock

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Synonyms	Atuliflapon
CAS No.	2041075-86-7
Purity	>98%
Formula	C24H26N6O3
Mol Weight	446.5016
Color	White to off-white
State	solid powder
Solubility	DMSO : 125 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Daniel Pettersen, et al. Discovery and Early Clinical Development of an Inhibitor of 5-Lipoxygenase Activating Protein (AZD5718) for Treatment of Coronary Artery Disease. J Med Chem. 2019 May 9;62(9):4312-4324.
CoA	CoA of AZD-5718

Smiles:	CC1=CC(=NN1)C2=CC=C(C=C2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4=C5C(=O)NCCN5N=C4


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