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Product Information:

AZ7550 hydrochloride

AZ7550 hydrochloride is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1.6 μM.

Cat. No.: EX-A6199A    Purity: >98%
Chemical
Chemical structure of AZ7550 hydrochloride


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg600in-stock
100mg800In-stock
250mg1300In-stock
500mg2300In-stock
1g3300In-stock


CAS No.2309762-40-9
Purity>98%
FormulaC27H32ClN7O2
Mol Weight522.042
ColorLight yellow to yellow
StateSolid
Solubilitysoluble in DMSO: 1.88 mg/mL (3.60 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Shelf Life>3 years if stored properly
StoragePowder 4℃, sealed storage, away from moisture, 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Finlay MR, et al. Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem. 2014 Oct 23;57(20):8249-67.

CoACoA of AZ7550 hydrochloride
Smiles:CNCCN(C1=CC(OC)=C(NC2=NC=CC(C3=CN(C)C4=CC=CC=C43)=N2)C=C1NC(C=C)=O)C.Cl

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