AZ3971

AZ3971 is an orally active, blood-brain barrier permeable BACE1 inhibitor that does not affect the activity of γ-secretase. AZ3971 reduces the production of Aβ. AZ3971 can be used for the research of Alzheimer's disease .


Cat. No.: EX-A8442	Purity: >98%

	Chemical structure of AZ3971

For research only, Do not use for Human!

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CAS No.	1260248-03-0
Purity	>98%
Formula	C25H22N6O
Mol Weight	422.4818

Reference:	[1].Strömberg K, et al. Combining an amyloid-beta (Aβ) cleaving enzyme inhibitor with a γ-secretase modulator results in an additive reduction of Aβ production. FEBS J. 2015 Jan;282(1):65-73.
CoA	CoA of AZ3971

Smiles:	NC1=N[C@@](C2=CC=CC(C3=CN=CN=C3)=C2)(C4=CC(C)=C(OC)C(C)=C4)C5=NC=CN=C51


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