AZ'4331

AZ'4331 is an orally active pan-TEAD family inhibitor, with an IC50 of 0.381 μM against TEAD1, 0.020 μM against TEAD2, 0.014 μM against TEAD3, and 0.031 μM against TEAD4. AZ'4331 slows cell cycle progression. AZ'4331 exerts effects in cancer xenograft models with dysregulated Hippo pathway. AZ'4331 can be used to study cancers with altered Hippo pathways, including mesothelioma, head and neck squamous cell carcinoma, and EGFR-mutant non-small cell lung cancer .


Cat. No.: EX-A17567	Purity:

	Chemical structure of AZ'4331

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
100mg	get quote
250mg	get quote
500mg	get quote

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	3006101-94-3
Formula	C21H18F3N5O
Mol Weight	413.3957

CoA	CoA of AZ'4331

Smiles:	C=CC(N(C1)CC[C@@H]1NC2=NC=C(C3=CC=C(C(F)(F)F)C=N3)C4=NC=CC=C42)=O


		Search