AZ-23

AZ-23 is an ATP-competitive and orally bioavailable Trk kinase A/B/C inhibitor with IC50s of 2 nM (TrkA), 8 nM (TrkB), 24 nM (FGFR1), 52 nM (Flt3), 55 nM (Ret), 84 nM (MuSk), 99 nM (Lck), respectively.


Cat. No.: EX-A5082	Purity: >98%

	Chemical structure of AZ-23

For research only, Do not use for Human!

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50mg	865	Inquire
100mg	1365	Inquire
1g	get quote

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Synonyms	AZ23
Synonyms 2	AZ 23
CAS No.	915720-21-7
Purity	>98%
Formula	C17H19ClFN7O
Mol Weight	391.83
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 125 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Thress K, et al. Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway. Mol Cancer Ther. 2009 Jul; 8(7):1818-27.
CoA	CoA of AZ-23

Smiles:	CC(OC1=CC(NC2=NC(N[C@H](C3=NC=C(F)C=C3)C)=NC=C2Cl)=NN1)C


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