AUTAC4

AUTAC4 is a mitochondria-targeting autophagy-targeting chimera (AUTAC). AUTAC4 downregulates cytosolic proteins and promotes targeted mitochondrial turnover via mitophagy.


Cat. No.: EX-A11350	Purity: >98%

	Chemical structure of AUTAC4

For research only, Do not use for Human!

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CAS No.	2267315-04-6
Purity	>98%
Formula	C43H48FN9O8S
Mol Weight	869.96
Color	White to light yellow
State	solid
Solubility	DMSO : 170 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Daiki Takahashi, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.
CoA	CoA of AUTAC4

Smiles:	CC(=O)N[C@@H](CSC1=NC2=C(N1CC3=CC=C(C=C3)F)N=C(NC2=O)N)C(=O)NCCCOCCOCCOCCCNC(=O)C(=O)C4=C(NC5=CC=CC=C54)C6=CC=CC=C6


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